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Table 1 Table of cytotoxic drugs that induce TNF-alpha and are enhanced in their activity with TNF-alpha

From: Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Anti-neoplastic drug

Class

Enhanced with TNF-alpha

Paclitaxel (taxol)

Diterpene

Yes

Doxorubicin

Anthracycline

Yes

Cytoxan

Cyclophosphamide

Yes

Gemcitabine

Nucleoside analogue

Yes

Cytarabine

Nucleoside analogue

Yes

Melphalan

Nitrogen mustard

Yes