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Table 4 Baseline serum cytokine levels in EV patients grouped by their CCR5 genotype

From: CCR5del32 genotype in human enteroviral cardiomyopathy leads to spontaneous virus clearance and improved outcome compared to wildtype CCR5

Cytokine serum levels (mean ± SD, pg/mL)

CCR5del32 hetero- or homozygous (n = 20)

CCR5 wildtype (n = 77)

Student’s t-test p value

IL1b

3.39 ± 7.35

8.18 ± 19.64

0.425

IL4

0.42 ± 0.74

6.68 ± 31.56

0.486

IL5

0.58 ± 1.04

1.08 ± 2.40

0.487

IL6

23.62 ± 19.20

132.50 ± 512.10

0.455

IL7

2.56 ± 2.03

4.08 ± 8.27

0.530

IL8

3.49 ± 2.86

7.27 ± 10.44

0.213

IL10

2.70 ± 3.38

12.56 ± 52.23

0.507

IL12p70

1.58 ± 2.34

11.17 ± 37.54

0.371

IL13

1.3 ± 1.92

7.05 ± 35.54

0.570

IL17

3.53 ± 3.71

4.49 ± 9.37

0.730

G-CSF

13.15 ± 16.06

27.25 ± 89.40

0.585

GM-CSF

75.12 ± 184.09

128.50 ± 563.16

0.546

IFNγ

22.10 ± 29.66

105.45 ± 463.46

0.415

MCP-1 (MCAF)

57.10 ± 89.03

48.61 ± 119.35

0.792

MIP-1β

41.06 ± 27.16

43.39 ± 62.13

0.892

TNFα

4.70 ± 6.26

10.80 ± 29.76

0.478

  1. IL interleukin, G-CSF granulocyte-colony stimulating factor, GM-CSF granulocyte–macrophage colony-stimulating factor, IFN interferon, MCP monocyte chemo attractant protein, MIP macrophage inflammatory protein, TNF tumour necrosis factor