Fig. 6

Cytotoxic effects of the HBx protein in response to blue light exposure in retinal epithelial cells. The cell viability and clonogenic survival were determined by the MTT assay and colony formation assay, respectively. a ARPE19 stable transfectants with or without HBx were exposed to the indicated dose of blue light. Cell viability was examined after 72 h. b, c Cells were exposed to increased doses of blue light, and clonogenic survival was determined after 2 weeks. The representative result is shown in (b), and the quantitative result from three independent experiments is shown in (c). Data are presented as mean ± SD. The symbols *P < 0.05 and **P < 0.01, respectively, compared with the mock-transfectant