Fig. 2

Expression of citrullinated proteins in gingival tissue samples of patients with and without periodontitis. a Representative immunohistochemical staining of citrullinated proteins in gingival tissue sections obtained from patients with periodontitis and periodontally healthy controls (non-periodontitis). Magnification ×250 (scale bars 100 μm). b Graph shows mean positive cell scores of citrullinated proteins (F95)-positive cells (± SD), stained in gingival tissue sections obtained from patients with periodontitis (n = 15) and non-periodontitis subjects (n = 15). E epithelium, CT connective tissue. **p < 0.01. c Immunohistochemical staining of synovial tissue used as positive control for citrullinated proteins. Magnification ×100 (scale bars 100 μm)