Table 2 Differentially gene expression in the TGFβ-signaling pathway

BMP5

(0.14, 0.21)

3.54E−39

BMP6

(0.21, 0.30)

2.55E−35

IFNG

(0.22, 0.45)

2.10E−09

BMP2

(0.28, 0.36)

2.85E−41

CDKN2B

(0.29, 0.37)

1.57E−41

GDF7

(0.32, 0.51)

9.55E−13

AMHR2

(0.24, 0.78)

7.72E−03

LEFTY2

(0.31, 0.60)

2.11E−06

ACVR1C

(0.43, 0.60)

2.99E−13

LEFTY1

(0.40, 0.65)

1.84E−07

FST

(0.45, 0.76)

1.21E−04

GDF6

(0.42, 0.83)

3.37E−03

THBS1

(0.61, 0.72)

1.76E−17

MAPK3

(0.62, 0.73)

4.62E−18

SMAD1

(0.67, 0.80)

1.75E−11

CHRD

(0.62, 0.87)

4.89E−04

SMAD4

(0.71, 0.80)

3.59E−16

SMAD7

(0.70, 0.85)

1.05E−06

SMAD9

(0.68, 0.91)

1.62E−03

ZFYVE9

(0.74, 0.86)

2.93E−08

ID3

(0.73, 0.91)

6.80E−04

SMAD2

(0.78, 0.88)

4.56E−09

ACVR1B

(0.78, 0.90)

1.88E−06

NBL1

(0.80, 0.91)

4.56E−06

SMAD3

(0.80, 0.91)

2.27E−06

PPP2CB

(0.79, 0.92)

8.37E−05

EP300

(0.84, 0.90)

8.90E−14

RPS6KB2

(0.82, 0.93)

1.16E−04

ACVR2A

(0.82, 0.98)

1.70E−02

RBX1

(0.82, 0.97)

1.35E−02

BMP8B

(0.81, 0.98)

2.30E−02

NODAL

(0.71, 1.14)

4.10E−01

INHBE

(0.67, 1.30)

7.08E−01

TNF

(0.72, 1.27)

7.71E−01

CREBBP

(0.93, 1.00)

7.19E−02

ROCK1

(0.91, 1.02)

2.61E−01

DCN

(0.84, 1.12)

7.08E−01

GDF5

(0.58, 1.70)

9.72E−01

ZFYVE16

(0.95, 1.07)

8.66E−01

MAPK1

(0.98, 1.07)

3.91E−01

TGFB1

(0.94, 1.17)

3.99E−01

SMURF1

(1.00, 1.12)

4.85E−02

PPP2R1B

(1.00, 1.13)

5.57E−02

SP1

(1.03, 1.12)

4.71E−04

ID2

(0.98, 1.22)

1.41E−01

TGFBR2

(1.03, 1.18)

7.47E−03

PPP2R1A

(1.07, 1.17)

1.18E−05

BMPR1A

(1.01, 1.24)

3.21E−02

SKP1

(1.06, 1.19)

1.28E−04

PPP2CA

(1.06, 1.20)

1.85E−04

BMPR1B

(0.85, 1.51)

4.18E−01

TGFB3

(1.01, 1.35)

4.71E−02

ACVR1

(1.08, 1.28)

4.18E−04

ID4

(1.00, 1.39)

6.14E−02

ID1

(1.00, 1.39)

5.57E−02

PITX2

(0.90, 1.59)

2.34E−01

RPS6KB1

(1.13, 1.30)

4.70E−07

BMP8A

(1.03, 1.46)

2.56E−02

E2F4

(1.17, 1.31)

1.97E−11

ACVR2B

(1.12, 1.36)

3.44E−05

BMPR2

(1.17, 1.32)

1.08E−10

LTBP1

(1.13, 1.40)

7.76E−05

SMAD6

(1.15, 1.44)

2.26E−05

SMAD5

(1.24, 1.41)

3.30E−15

SMURF2

(1.24, 1.45)

1.04E−11

RHOA

(1.29, 1.42)

4.34E−26

CUL1

(1.31, 1.50)

9.04E−19

E2F5

(1.38, 1.67)

3.20E−15

TGFBR1

(1.40, 1.65)

3.31E−18

TGIF1

(1.49, 1.75)

7.21E−24

AMH

(1.37, 2.22)

1.63E−05

BAMBI

(1.48, 2.30)

2.72E−07

INHBB

(1.52, 2.39)

1.43E−07

TGFB2

(1.71, 2.44)

2.96E−13

BMP4

(1.88, 2.52)

6.72E−20

TFDP1

(2.03, 2.39)

1.55E−47

RBL1

(2.08, 2.54)

4.37E−39

TGIF2

(2.33, 2.88)

5.45E−42

MYC

(3.28, 4.17)

2.33E−53

BMP7

(3.34, 5.20)

4.84E−27

INHBA

(7.67, 11.39)

5.94E−56