Fig. 4

Frequencies of CD4+CD25hiFoxp3+ Treg and CD4+CD25hiCD39+ Treg from baseline through 9 months in patients who did not relapse or relapsed at 9 months. The solid blue line represents the median value of Treg for the relapse-free group, and the solid red line represents the median value for the relapsed group. a The levels of CD4+CD25hiFoxp3+ Treg increased at 6 weeks in both groups but returned to almost baseline levels starting 3 months. There were no significant differences in CD4+CD25hiFoxp3+ Treg between the two groups at baseline, 3, 6, or 9 months. b At 3 months, levels of CD4+CD25hiCD39+ Treg returned nearly to baseline. There were no significant differences in Treg levels between the two groups starting at 3 months