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Table 4 Univariate and multivariate analysis for clinicopathologic variables

From: Nuclear Klf4 accumulation is associated with cetuximab drug-resistance and predicts poor prognosis of nasopharyngeal carcinoma

Parameters

HR

Univariate analysis

HR

Multivariate analysis

95% CI

P a

95% CI

P a

Gender

 Male vs. female

0.889

0.763–2.111

0.346

   

Age (years)

 < 52 vs. ≥ 52

0.385

0.753–2.217

0.535

   

T classification

 T3 vs. T4

1.635

1.413–2.299

0.201

   

N classification

 N0 vs. N1–3

2.453

0.916–2.054

0.117

   

M classification

 M0 vs. M1

1.745

0.761–1.777

0.187

   

C classification

 III vs. IV

0.337

1.244–2.170

0.562

   

nKlf4

 Low and high

1.616

1.106–2.361

0.013

0.608

0.406–0.909

0.015

cKlf4

 Low and high

0.591

0.395–0.884

0.056

0.596

0.398–0.892

0.027

nEGFR

 Low and high

1.461

1.002–1.920

0.049

1.534

1.050–2.239

0.027

cMET

 Low and high

1.254

0.744–1.734

0.043

1.324

0.773–1.875

0.032

PI3K

 Positive and negative

3.029

2.430–3.628

0.034

1.236

0.544–1.928

0.000

H-Ras

 Positive and negative

1.664

1.050–2.278

0.030

1.298

0.768–1.828

0.000

  1. HR hazard rate, CI confidence interval
  2. aCox regression model
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Journal of Translational Medicine

ISSN: 1479-5876

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