Fig. 5

Survival of the patients with GBM based on the CMV- and EBV-specific IFNγ production. Kaplan–Meier curve shows the overall survival of GBM patients with detectable IFNγ response. Median concentration of detectable virus-specific IFNγ production was used as a cut-off to generate two separate groups: “< median” and “> median” antigen-specific response. a–d IFNγ production without IL-2/IL-15/IL-21 cytokine conditioning a, b Survival based on the absolute IFNγ production in response to CMV-pp65 (n = 56) and EBNA-1 (n = 61). c, d Survival based on the relative IFNγ production in response to CMV-pp65 (n = 56) and EBNA-1 (n = 61). e–h IFNγ production with IL-2/IL-15/IL-21 cytokine conditioning e, f Survival based on the absolute IFNγ production in response to CMV-pp65 (n = 108) and EBNA-1 (n = 117). g, h Survival based on the relative IFNγ production in response to CMV-pp65 (n = 108) and EBNA-1 (n = 117). Post-OP post-operation