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Table 3 Cytokine secretion by peripheral monocytes

From: Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Cytokine (stimulant)

Baseline

3 months after CPB

Mean

SD

Mean

SD

IL-1β (LPS)

23,886.4

26,986.1

13,108.4

10,949.3

IL-1β (P&I)

7196.9

4388.7

8363.2

6840.8

IL-6 (LPS)

101,496.5

19,494.2

56,470.2

47,780.5

IL-6 (P&I)

38,233.9

12,750.2

52,475.5

41,079.9

IL-10 (LPS)

57,437.3

65,227.8

13,228.6

16,455.6

IL-10 (P&I)

4948.5

2698.2

11,942.9

9126.7

TNFα (LPS)

127,605.4

56,909.5

89,928.2

67,496.8

TNFα (P&I)

33,291.7

15,980.3

67,759.4

59,473.3

  1. Secretion of IL-1β, IL-6, IL-10, and TNFα by peripheral blood monocytes was not significantly different 3 months after CPB in response to either LPS or combination of PMA and ION (stimulant denoted by parentheses).
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Journal of Translational Medicine

ISSN: 1479-5876

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