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Table 3 Cytokine secretion by peripheral monocytes

From: Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Cytokine (stimulant) Baseline 3 months after CPB
Mean SD Mean SD
IL-1β (LPS) 23,886.4 26,986.1 13,108.4 10,949.3
IL-1β (P&I) 7196.9 4388.7 8363.2 6840.8
IL-6 (LPS) 101,496.5 19,494.2 56,470.2 47,780.5
IL-6 (P&I) 38,233.9 12,750.2 52,475.5 41,079.9
IL-10 (LPS) 57,437.3 65,227.8 13,228.6 16,455.6
IL-10 (P&I) 4948.5 2698.2 11,942.9 9126.7
TNFα (LPS) 127,605.4 56,909.5 89,928.2 67,496.8
TNFα (P&I) 33,291.7 15,980.3 67,759.4 59,473.3
  1. Secretion of IL-1β, IL-6, IL-10, and TNFα by peripheral blood monocytes was not significantly different 3 months after CPB in response to either LPS or combination of PMA and ION (stimulant denoted by parentheses).