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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Acquired immunological imbalance after surgery with cardiopulmonary bypass due to epigenetic over-activation of PU.1/M-CSF

Fig. 4

Expression of M-CSF receptor significantly increases and persists after CPB. a The expression of M-CSF receptors in terms of positive cells was not significantly different in a group analysis on the surface of circulating MO. b The CD115/M-CSFR receptor density was significantly increased at all times vs baseline after the surgery t0: Me = 2314.64; IQR[1032.07, 4978.19] t24h: Me = 10,425.65; IQR[8041.68, 16,667.99]; ΔRank = − 22.50; CI 95%  = [− 35.59, − 9.41]; p = 0.002; CLES = 0.82; t7d: Me = 12,824.02; IQR[4165.53, 16,443.61]; ΔRank = − 18.5; CI 95%  = [− 31.59, − 5.41]; p = 0.007; CLES = 0.82; t3m: Me = 9858.70; IQR[7541.30, 16,547.60] ΔRank = − 25.00; CI 95%  = [− 38.09, − 11.91]; p = 0.001; CLES = 0.82. Asterisk indicate data points which were significantly different when compared vs baseline. CI 95% : 95% confidence interval for difference in sum of ranks. CLES: common language effect size

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