Samples | Total SNPs | Fraction of SNPs in dbSNP (%) | Fraction of SNPs in 1000 genomes (%) | Novel | Homozygous | Heterozygous | Intron | 5′ UTRs | 3′ UTRs | Upstream | Down stream | Intergenic | Ti/Tv |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Patient tumor tissue | 102,402 | 98.23 | 95.81 | 1473 | 1473 | 54,009 | 69,062 | 1567 | 3298 | 2077 | 1538 | 2330 | 2.34 |
Primary cell line | 94,847 | 98.23 | 95.81 | 1473 | 44,541 | 50,306 | 62,661 | 1426 | 2974 | 1793 | 1377 | 2188 | 2.35 |
PDX tumor tissue | 95,908 | 94.59 | 92.17 | 1473 | 44,875 | 51,033 | 61,376 | 1468 | 3130 | 1778 | 1359 | 2170 | 2.33 |