Fig. 1

The schematic pipeline for MPCa microRNA biomarker identification. LIMMA linear models for microarray data analysis; eBayes the empirical bayes; adj.p value adjusted p value; FC fold change; DE differentially expressed; MicroRNA-BD microRNA biomarker discovery; NSR number of single-line regulation; TFP transcription factor gene percentage; UTP percentage of transcription factor genes in microRNA unique targets; ROC receiver operating characteristic curve; GO Gene Ontology; MPCa metastatic prostate cancer