Fig. 5
a MIV-711 concentrations in human plasma at various time points after a single dose. b CTX-I levels were measured in serum at various time points after a single dose. c Relationship between MIV-711 exposure (AUC0–24h) and % inhibition of serum CTX-I at 24 h post-dose. d Exposure-efficacy comparison between monkey and human. Grouped data are expressed as Mean ± SEM, n = 7–10