Table 4 Multivariate Cox regression analysis (overall survival) for the histopathological response and non-response (tumor regression), pathologic tumor stage (UICC ypT category), lymph node status (ypN), distant metastasis, and miRNA-194* and miRNA-665 expression levels
Factor | HR | 95.0% CI for HR | p value | p value | |
|---|---|---|---|---|---|
Min | Max | Univariate | |||
Tumor regression | 5.681 | 0.507 | 63.709 | 0.159 | < 0.001 |
UICC ypT category | 1.460 | 0.724 | 2.947 | 0.290 | < 0.001 |
Lymph node metastases | 7.561 | 1.631 | 35.062 | 0.010 | < 0.001 |
Distant metastasis | 1.666 | 0.243 | 11.442 | 0.603 | < 0.001 |
Resection status | 0.384 | 0.112 | 1.315 | 0.128 | 0.0120 |
miRNA-194* | 0.669 | 0.133 | 3.352 | 0.625 | 0.052 |
miRNA-665 | 0.634 | 0.104 | 3.861 | 0.621 | 0.197 |