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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Novel oncolytic chimeric orthopoxvirus causes regression of pancreatic cancer xenografts and exhibits abscopal effect at a single low dose

Fig. 1

Novel chimeric orthopoxvirus isolates CF33 and CF17 show superior cancer cell killing capability compared to the parental individual wild-type virus strains. Fifty-four solid cancer cell lines in the NCI-60 panel were infected with each virus at an MOI of 0.01. Cell viability was measured at 96 h post infection using MTS assays. Data represent the mean cell survival of 54 cancer cell lines ± sd. CF17 and CF33 demonstrated significantly better cell killing (p < 0.001) in the NCI-60 solid tumor cell lines than all nine parental orthopoxvirus strains

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Journal of Translational Medicine

ISSN: 1479-5876

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