Table 3 Comparative analysis of the clinicopathological factors according to the expression of GLUT-1
Variables | GLUT-1 Low n = 24 (48.0%) | GLUT-1 High n = 26 (52.0%) | Univariable P* |
|---|---|---|---|
Clinical factors | |||
 Sex | |||
  Male/female | 13/11 | 16/10 | 0.775 |
 Age (years) | 68 (32 − 83) | 70 (46 − 81) | 0.303 |
 CEA (ng/mL) | 2.8 (0.4 − 8.8) | 3.6 (0.7 − 133.1) | 0.265 |
 CA19-9 (IU/mL) | 38.7 (0.7 − 766) | 65.5 (0.8 − 3055) | 0.593 |
 SUVmax | 4.5 (2.9 − 9.2) | 7.0 (3.6 − 14.7) | < 0.001 |
 MTV (cm3) | 8.4 (1.5 − 604.0) | 72.0 (3.6 − 777.0) | 0.008 |
 TLG (g) | 20.2 (3.6 − 3201.2) | 259.2 (27.0 − 3418.8) | < 0.001 |
 Tumor size (cm) | |||
  Radiographical | 3.5 (1.0 − 11.0) | 4.0 (1.0 − 14.0) | 0.108 |
Treatment factors | |||
 R0 resection, n (%) | 23 (95.8) | 25 (96.2) | 1.000 |
 Minor hepatectomy, n (%) | 4 (16.7) | 2 (7.7) | 0.409 |
 Morbidity | |||
  C-D class III/IV, n (%) | 5 (20.8) | 7 (26.9) | 0.745 |
 Preoperative chemotherapy | |||
  Present, n (%) | 0 | 0 | 0 |
 Adjuvant chemotherapy | |||
  Present, n (%) | 17 (70.8) | 13 (50.0) | 0.159 |
Pathological factors | |||
 Tumor differentiation | |||
  Well/moderate, n (%) | 22 (91.7) | 21 (80.8) | 0.420 |
  Poor, n (%) | 2 (8.3) | 5 (19.2) |  |
 Vascular invasion | |||
  Present, n (%) | 18 (75.0) | 16 (61.5) | 0.372 |
 Bile duct invasion | |||
  Present, n (%) | 11 (45.8) | 13 (50.0) | 0.785 |
 Lymph node metastasis | |||
  Present, n (%) | 7 (29.2) | 8 (30.8) | 1.000 |
 Tumor number | |||
  Multiple, n (%) | 2 (8.3) | 13 (50.0) | 0.002 |
 Tumor size (cm) (pathological) | 3.2 (1.0 − 10.8) | 4.0 (1.2 − 14.0) | 0.073 |
 AJCC stage | |||
  IV, n (%) | 8 (33.3) | 17 (65.4) | 0.047 |