Fig. 2

Correlations of urinary or plasma miR-196a levels with the disease activity. a Urinary miR-196a levels in different groups. ROC curve analysis indicates that urinary miR-196a can distinguish FSGS-A patients from normal controls (b) and FSGS-CR patients (c) with high sensitivity and specificity. d Plasma miR-196a levels in different groups. ROC curve analysis indicates that plasma miR-196a could not distinguish FSGS-A patients from normal controls (e) and FSGS-CR patients (f). Note that no significant correlation was seen between plasma miR-196a level and the disease activity. Bars indicate median with inter-quartile range. NC normal controls, FSGS-A FSGS patients with nephrotic-range proteinuria, FSGS-CR FSGS in complete remission, AUC area under the receiver operating characteristic curve, ROC receiver operating characteristic curve