Fig. 6

YM155 increases the antitumor effect of radiotherapy in vivo. a Survival curve of animals implanted with U251 cells in the four different treatment groups indicated. b Representative images of hematoxylin and eosin staining of brain sections from animals in each of the four different treatment groups indicated. c IHC for pSTAT3 (Ser727) and pSTAT3 (Tyr705) in xenograft sections from animals in each of the four different treatment groups. Quantitation of positive staining nuclei. Positively staining cells are presented as a percentage of total number of cells counted. **P < 0.01; size bars = 50 µm. d Representative images of subcutaneous tumors with U87 cells. Tumor volume and tumor weight were measured. **P < 0.01