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Table 2 Overall survival analyses for CN-AML patients

From: MiR-362-5p as a novel prognostic predictor of cytogenetically normal acute myeloid leukemia

Variables

Univariate analysis

Multivariate analysis

P value

HR (95%)

P value

HR (95%)

miR-362-5p

0.028

1.615 (1.048, 2.488)

0.045

1.599 (1.011, 2.528)

WBC

< 0.001

1.005 (1.003, 1.008)

< 0.001

1.006 (1.003, 1.009)

Hemoglobin

0.242

0.995 (0.987, 1.003)

0.297

0.995 (0.987, 1.004)

Age

0.006

1.02 (1.006, 1.035)

0.005

1.022 (1.007, 1.038)

FLT3-ITD

0.654

1.136 (0.65, 1.987)

0.723

1.11 (0.622, 1.982)

CEBPADM&

0.014

0.352 (0.153, 0.809)

0.007

0.312 (0.133, 0.732)

NPM1

0.884

1.038 (0.629, 1.712)

0.039

0.547 (0.309, 0.969)

DNMT3A

0.157

1.58 (0.838, 2.979)

0.356

1.376 (0.699, 2.711)

IDH1

0.043

1.879 (1.019, 3.466)

0.125

1.662 (0.868, 3.183)

IDH2

0.613

0.849 (0.45, 1.601)

0.196

0.644 (0.331, 1.254)

  1. MiR-362-5p: high vs low expression, Age, WBC and hemoglobin are used as continuous variables
  2. DM& double allele mutations