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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Oral Escherichia coli expressing IL-35 meliorates experimental colitis in mice

Fig. 2

IL-35 ameliorates symptoms of DSS-induced colitis. Body weight (a) and disease activity index (DAI) (b) change of each group. DSS + E. coli/IL-35 group showed less body weight loss and much lower DAI score. Data were presented as the mean ± SD (n = 10 per group). Compared with the DSS group, *p < 0.05; compared with the DSS + E. coli/0 group, *p < 0.05. c The length of mouse colon from normal group, DSS group, DSS + E. coli/0 group and DSS + E. coli/IL-35 groups. *p < 0.05, E. coli/IL-35 group vs. DSS and DSS + E. coli/0 group. d Representative photomicrographs (×200, haematoxylin and eosin staining) of histological sections of colon from each group. n = 10 mice per group. *p < 0.05, E. coli/IL-35 group vs. DSS and DSS + E. coli/0 group

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