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Table 3 Scripps neurological rating system (SRNS) component scores

From: Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis

SNRS component

Baseline

1 month

1 year

Mentation and mood (normal = 10)

8.4 (2.28)

9.4 (1.57)

9.3 (1.69)

Visual acuity (normal = 5)*

4.9 (0.45)

4.2* (1.35)

4.2* (1.24)

Visual fields (normal = 6)

5.7 (0.73)

5.6 (1.05)

5.6 (0.79)

Eye movements (normal = 5)

4.8 (0.62)

4.8 (0.62)

4.8 (0.66)

Nystagmus (normal = 5)

5.0 (0.00)

4.8 (0.62)

4.9 (0.49)

Lower cranial nerves (normal = 5)

5.0 (0.00)

4.9 (0.45)

5.0 (0.0)

Motor function R upper extremity (normal = 5)*

4.8 (0.62)

4.5 (0.89)

4.1* (1.44)

Motor function L upper extremity (normal = 5)

4.3 (0.98)

4.4 (1.14)

4.1 (1.44)

Motor function R lower extremity (normal = 5)

3.2 (1.66)

2.6 (1.82)

2.4 (1.91)

Motor function L lower extremity (normal = 5)

2.7 (1.81)

2.7 (2.03)

2.7 (2.23)

DTR upper extremity (normal = 4)

3.6 (0.95)

3.3 (1.22)

3.6 (0.79)

DTR lower extremity (normal = 4)

2.4 (1.35)

2.1 (1.62)

2.3 (1.61)

Babinski sign L side (absent = 2)

0.6 (0.94)

0.9 (1.02)

0.7 (0.99)

Babinski sign R side (absent = 2)

0.8 (1.01)

0.8 (1.01)

0.5 (0.87)

Sensory R upper extremity (normal = 3)

3.0 (0.00)

2.7 (0.47)

2.8 (0.56)

Sensory L upper extremity (normal = 3)

3.0 (0.00)

2.6 (0.50)

2.8 (0.56)

Sensory R lower extremity (normal = 3)*

2.9 (0.31)

2.5* (0.51)

2.5* (0.72)

Sensory L lower extremity (normal = 3)

2.9 (0.31)

2.5* (0.51)

2.5 (0.80)

Cerebellar signs upper extremity (normal = 5)

4.0 (1.52)

4.0 (1.52)

4.1 (1.60)

Cerebellar signs lower extremity (normal = 5)

2.9 (1.46)

3.6 (1.87)

3.4 (1.77)

Gait trunk and balance (normal = 10)

5.1 (2.74)

5.6 (3.17)

4.6 (3.69)

Bladder, bowel, and/or sexual dysfunction (normal = 0)*

− 4.7 (2.52)

− 2.7* (2.89)

− 3.1 (3.31)

Total SNRS

75.0 (11.90)

75.5 (16.54)

73.5 (19.52)

  1. *Statistically significant change, p < 0.05