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Table 3 Scripps neurological rating system (SRNS) component scores

From: Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis

SNRS component Baseline 1 month 1 year
Mentation and mood (normal = 10) 8.4 (2.28) 9.4 (1.57) 9.3 (1.69)
Visual acuity (normal = 5)* 4.9 (0.45) 4.2* (1.35) 4.2* (1.24)
Visual fields (normal = 6) 5.7 (0.73) 5.6 (1.05) 5.6 (0.79)
Eye movements (normal = 5) 4.8 (0.62) 4.8 (0.62) 4.8 (0.66)
Nystagmus (normal = 5) 5.0 (0.00) 4.8 (0.62) 4.9 (0.49)
Lower cranial nerves (normal = 5) 5.0 (0.00) 4.9 (0.45) 5.0 (0.0)
Motor function R upper extremity (normal = 5)* 4.8 (0.62) 4.5 (0.89) 4.1* (1.44)
Motor function L upper extremity (normal = 5) 4.3 (0.98) 4.4 (1.14) 4.1 (1.44)
Motor function R lower extremity (normal = 5) 3.2 (1.66) 2.6 (1.82) 2.4 (1.91)
Motor function L lower extremity (normal = 5) 2.7 (1.81) 2.7 (2.03) 2.7 (2.23)
DTR upper extremity (normal = 4) 3.6 (0.95) 3.3 (1.22) 3.6 (0.79)
DTR lower extremity (normal = 4) 2.4 (1.35) 2.1 (1.62) 2.3 (1.61)
Babinski sign L side (absent = 2) 0.6 (0.94) 0.9 (1.02) 0.7 (0.99)
Babinski sign R side (absent = 2) 0.8 (1.01) 0.8 (1.01) 0.5 (0.87)
Sensory R upper extremity (normal = 3) 3.0 (0.00) 2.7 (0.47) 2.8 (0.56)
Sensory L upper extremity (normal = 3) 3.0 (0.00) 2.6 (0.50) 2.8 (0.56)
Sensory R lower extremity (normal = 3)* 2.9 (0.31) 2.5* (0.51) 2.5* (0.72)
Sensory L lower extremity (normal = 3) 2.9 (0.31) 2.5* (0.51) 2.5 (0.80)
Cerebellar signs upper extremity (normal = 5) 4.0 (1.52) 4.0 (1.52) 4.1 (1.60)
Cerebellar signs lower extremity (normal = 5) 2.9 (1.46) 3.6 (1.87) 3.4 (1.77)
Gait trunk and balance (normal = 10) 5.1 (2.74) 5.6 (3.17) 4.6 (3.69)
Bladder, bowel, and/or sexual dysfunction (normal = 0)* − 4.7 (2.52) − 2.7* (2.89) − 3.1 (3.31)
Total SNRS 75.0 (11.90) 75.5 (16.54) 73.5 (19.52)
  1. *Statistically significant change, p < 0.05