Fig. 5
From: The role of atorvastatin in suppressing tumor growth of uterine fibroids
Effect of atorvastatin on MAPK pathway protein in human uterine fibroids cells. a Related MAPK pathway protein changed after treated with 5 μM atorvastatin for 48 h in immortalized human uterine fibroids cells (Human Phospho-MAPK Antibody Array). b, c Effects of atorvastatin on the expression of p-ERK1/2 and ERK1/2 proteins in immortalized cells and primary cells, respectively. d Effects of atorvastatin on the expression of p-JNK and JNK proteins in primary cells, respectively. Tubulin was used as the loading control. The intensity of each protein band was quantified and normalized with corresponding tubulin, and the normalized values were used to generate the graphs. Data presented were mean ± SEM from triplicate measurements. *P < 0.05 with one-way ANOVA