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Table 3 Significant negative correlation between the identified miRNA and mRNA by microarray (un-paired two-tailed t test < 0.5/> 1.5-fold difference, P < 0.05)

From: Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome

miRNA mRNA P value correlation Correlation Fold change miRNA P value miRNA Fold change mRNA P value mRNA
hsa-miR-1234 LIMK2 0.00001 − 0.89 0.12 0.00038 2.22 0.01813
hsa-miR-1234 DYSF 0.00018 − 0.85 0.12 0.00038 2.74 0.01491
hsa-miR-1234 GBP2 0.00143 − 0.78 0.12 0.00038 2.04 0.00973
hsa-miR-1234 MMP9 0.00382 − 0.74 0.12 0.00038 2.15 0.03885
hsa-miR-324-5p POT1 0.00670 − 0.69 1.72 0.00050 0.47 0.00017
hsa-miR-151-5p POT1 0.00728 − 0.68 1.73 0.01754 0.47 0.00017
hsa-miR-200c POT1 0.01132 − 0.65 43.66 0.01425 0.47 0.00017
hsa-miR-362-5p POT1 0.01281 − 0.64 1.52 0.00045 0.47 0.00017
hsa-miR-502-3p POT1 0.01590 − 0.63 1.58 0.00054 0.47 0.00017
hsa-miR-500b POT1 0.01868 − 0.62 48.35 0.01419 0.47 0.00017
hsa-miR-627 POT1 0.01868 − 0.62 33.47 0.03109 0.47 0.00017