Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome

Table 3 Significant negative correlation between the identified miRNA and mRNA by microarray (un-paired two-tailed t test < 0.5/> 1.5-fold difference, P < 0.05)

miRNA	mRNA	P value correlation	Correlation	Fold change miRNA	P value miRNA	Fold change mRNA	P value mRNA
hsa-miR-1234	LIMK2	0.00001	− 0.89	0.12	0.00038	2.22	0.01813
hsa-miR-1234	DYSF	0.00018	− 0.85	0.12	0.00038	2.74	0.01491
hsa-miR-1234	GBP2	0.00143	− 0.78	0.12	0.00038	2.04	0.00973
hsa-miR-1234	MMP9	0.00382	− 0.74	0.12	0.00038	2.15	0.03885
hsa-miR-324-5p	POT1	0.00670	− 0.69	1.72	0.00050	0.47	0.00017
hsa-miR-151-5p	POT1	0.00728	− 0.68	1.73	0.01754	0.47	0.00017
hsa-miR-200c	POT1	0.01132	− 0.65	43.66	0.01425	0.47	0.00017
hsa-miR-362-5p	POT1	0.01281	− 0.64	1.52	0.00045	0.47	0.00017
hsa-miR-502-3p	POT1	0.01590	− 0.63	1.58	0.00054	0.47	0.00017
hsa-miR-500b	POT1	0.01868	− 0.62	48.35	0.01419	0.47	0.00017
hsa-miR-627	POT1	0.01868	− 0.62	33.47	0.03109	0.47	0.00017

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