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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Physiological and molecular effects of interleukin-18 administration on the mouse kidney

Fig. 2

No side effects were observed with rIL-18 administration for 2 weeks. To analyze the effects on renal function, mice were injected with rIL-18 twice a week for 2 weeks from 10 weeks of age (short-term treatment). Serum levels of BUN (a) and CREA (b) are shown. Data are mean ± SD (a, b: n = 8 per group). c Hematoxylin–eosin, d periodic acid–Schiff, and e periodic acid methenamine silver staining. Scale bars represent 50 μm (ce). BUN: blood urea nitrogen; CREA: creatinine

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