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Table 2 Association of biological measures with illness groups: selected measures included telomere length, metabolic, and allostatic load variables

From: Association of chronic fatigue syndrome with premature telomere attrition

Variable

All

(n = 639)

CFS-X

(n = 77)

CFS

(n = 64)

ISF

(n = 302)

NF

(n = 196)

p-value

T/S ratio telomere lengtha

0.98 (0.01)

0.97 (0.04)

0.90 (0.03)

0.94 (0.02)

1.06 (0.04)

0.0017

Triglycerides (mg/dL)b

117.13 (3.51)

144.01 (12.15)

143.53 (16.4)

114.25 (4.81)

102.43 (4.62)

0.0003

HDL (mg/dL)b,c

53.86 (0.65)

54.45 (2.29)

52.06 (1.92)

53.31 (0.91)

55.05 (1.16)

0.5278

Heart rate (bpm)c

68.02 (0.35)

69.91 (1.01)

69.05 (1.2)

68.33 (0.5)

66.47 (0.6)

0.0113

Blood pressure: systolic (mmHg)b,c

118.52 (0.61)

120.14 (1.99)

119.34 (1.91)

118.75 (0.92)

117.28 (0.95)

0.4935

Blood pressure: diastolic (mmHg)b,c

74.92 (0.39)

76.29 (1.29)

74.42 (1.32)

74.97 (0.56)

74.48 (0.66)

0.5685

Fasting glucose (mg/dL)b,c

94.35 (0.63)

96.68 (2.02)

93.36 (1.84)

95.5 (1.04)

91.98 (0.8)

0.0501

Insulin (µIU/mL)c

6.29 (0.26)

7.68 (0.92)

6.91 (0.74)

6.64 (0.39)

5.01 (0.39)

0.0062

CRP (mg/dL)c

3.62 (0.2)

5.1 (0.76)

4.71 (0.79)

3.73 (0.28)

2.54 (0.26)

0.0003

Albumin (g/dL)c

4.2 (0.01)

4.23 (0.03)

4.22 (0.03)

4.18 (0.01)

4.22 (0.02)

0.2336

  1. Values are mean (SEM) unless otherwise indicated
  2. aT/S ratio of a subject is the ratio of telomere PCR signal (T) to the single copy gene PCR signal (S). The T/S ratio is proportional to the average telomere length per cell and is expressed relative to the T/S ratio of a reference DNA
  3. bMetabolic syndrome variable
  4. cAllostatic load variable