Double-negative (CD27−IgD−) B cells are expanded in NSCLC and inversely correlate with affinity-matured B cell populations

Table 1 Clinical information associated with NSCLC patient cohort

Patient ID	Diagnosis	Age	Smoking status	Gender	Stage	Differentiation	% DN cells out of total live singlets
R160007	SqCC	70	Smoker	Female	Stage IB	Poorly differentiated	0.204
R160023	Adeno	86	Non-Smoker	Female	Stage IIB	Poorly differentiated	0.222
R160093	Sqcc	69	Smoker	Male	StageIB	Moderately differentiated	0.536
R170219	Sqcc	69	Smoker	Male	Stage IIIA	Poorly differentiated	0.643
R170133	Sqcc	62	Non-Smoker	Female	Stage IB	Poorly differentiated	0.985
R170188	Adeno	72	Smoker	Female	Stage IA	Poorly differentiated	1.088
R170018	Sqcc	74	Smoker	Female	Stage IIIA	Poorly differentiated	1.341
R170136	Sqcc	60	Smoker	Female	Stage IIIA	Moderately differentiated	1.721
R170062	Sqcc	83	Smoker	Male	Stage IB	Moderately differentiated	1.830
R150259	Sqcc	75	Smoker	Male	Stage IB	Poorly differentiated	1.943
R160116	Sqcc	73	Smoker	Male	Stage IIB	Poorly differentiated	1.969
R170016	Adeno	71	Non-Smoker	Female	Stage IB	Poorly differentiated	2.059
R160150	Adeno	71	Smoker	Female	Stage IB	Moderately differentiated	4.471
R160153	Adeno	84	Non-Smoker	Female	Stage IB	Moderately differentiated	6.269
R160250	Adeno	84	Non-Smoker	Male	Stage IIA	Moderately differentiated	8.492

Smoking status was defined as smoker including the groups current and former smoker and non-smoker including the groups non-smoker and never smokers
SqCC squamous cell carcinoma, Adeno adenocarcinoma

ISSN: 1479-5876