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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons

Fig. 2

Effect size estimates (\(\mu_{p}^{2}\) = partial eta squared) and confidence intervals (C.I.) for clinical, microbial and lactate outcomes for the total sample across time. The cut-off for large effects (\(\mu_{p}^{2}\) > .14) is indicated by the dotted line. Asterisks (*) are used to identify primary outcomes. Change in mean scores for all clinical outcomes (sleep, mood, cognitive and other) were in the direction of improvement at post-intervention. Change in mean scores on microbiota variables reduced at post-intervention unless indicated (^). The d:l lactate variable ratio increased at post-intervention (^). See Additional file 1: Table S1 for baseline and post descriptive statistics for each variable

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