Fig. 5

Verification of target proteins using MRM assay. a Heat map showing the change in abundance of differentially expressed proteins in HDC vs NDC, LDC vs NDC, and HDC vs LDC groups, as measured using MRM (left panel) and iTRAQ (right panel). The protein names corresponding to the accession according to Uniprot database were listed in Additional file 4: Table S5. b Venn diagram for the number of proteins verified by MRM commonly or exclusively among three comparison groups