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Table 1 Clinical and biochemical characteristics of study subjects without or with tendon xanthomas

From: Association between non-cholesterol sterol concentrations and Achilles tendon thickness in patients with genetic familial hypercholesterolemia

  FH
n = 103
Subjects without xanthomas
n = 63
Subjects with xanthomas
n = 40
p
Age, years 39.4 ± 13.2 40.7 ± 13.0 0.639
Men, n (%) 32 (50.8) 18 (45.0) 0.566
Current smokers, n (%) 19 (31.7) 7 (17.5) 0.286
Non-smokers, n (%) 30 (50.0) 24 (60)  
Former smokers, n (%) 11 (18.3) 9 (22.5)  
Carotid plaque, n (%) 9 (15.5) 5 (13.2) 0.674
Diabetes, n (%) 2 (3.2) 1 (2.5) 0.843
Hypertension, n (%) 7 (11.1) 3 (7.5) 0.546
Body mass index, Kg/m2 24.2 ± 3.7 25.0 ± 3.4 0.251
Corneal arcus, n (%) 11 (17.5) 23 (41.0) 0.009
Lipoprotein(a), mg/dl 27.6 (12.4–45.5) 26.0 (11.2–51.6) 0.994
Glucose, mg/dl 87 (81–93) 86 (80–95) 0.935
C-reactive protein, g/l 1.8 (0.5–3.4) 0.85 (0.52–2.1) 0.202
APOE genotype E3/3, n (%) 38 (60.3) 27 (69.2) 0.736
APOE genotype E3/2, n (%) 7 (11.1) 4 (10.3)  
APOE genotype E3/4, n (%) 17 (27.0) 7 (17.9)  
APOE genotype E2/4, n (%) 1 (1.6) 1 (2.6)  
  1. Numerical variables with normal distribution are expressed as mean ± standard deviation and those with skewed distribution are expressed as median [percentile 25–percentile 75]. t Student or Mann–Whitney or Chi square tests were used as appropriate