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Table 2 Summary of the GO and pathway analysis results of the four sepsis-associated modules

From: Identification of potential transcriptomic markers in developing pediatric sepsis: a weighted gene co-expression network analysis and a case–control validation study

Module GO (BP) GO (CC) GO (MF) KEGG pathway
Term Genes P Term Genes P Term Genes P Term Genes P
Midnight blue Cellular defense response 6 1.59 × 10−7 External side of plasma membrane 4 7.73 × 10−3 Carbohydrate binding 5 4.62 × 10−4 Natural killer cell mediated cytotoxicity 4 4.43 × 10−3
Cyan Innate immune response 5 9.49 × 10−3 Extracellular space 12 4.40 × 10−5 Ribonuclease activity 2 4.12 × 10−2 NA NA NA
Brown Inflammatory response 68 1.05 × 10−10 Extracellular exosome 346 3.36 × 10−24 Protein binding 810 2.55 × 10−11 Osteoclast differentiation 43 1.90 × 10−12
Tan Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 6 8.89 × 10−10 MHC class II protein complex 6 3.36 × 10−9 MHC class II receptor activity 5 1.17 × 10−7 Asthma 6 8.95 × 10−8
  1. GO gene ontology, BP biological process, CC cellular component, MF molecular function, KEGG Kyoto Encyclopedia of Genes and Genomes, NA not available