Table 2 Summary of the GO and pathway analysis results of the four sepsis-associated modules
Module | GO (BP) | GO (CC) | GO (MF) | KEGG pathway | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Term | Genes | P | Term | Genes | P | Term | Genes | P | Term | Genes | P | |
Midnight blue | Cellular defense response | 6 | 1.59 × 10−7 | External side of plasma membrane | 4 | 7.73 × 10−3 | Carbohydrate binding | 5 | 4.62 × 10−4 | Natural killer cell mediated cytotoxicity | 4 | 4.43 × 10−3 |
Cyan | Innate immune response | 5 | 9.49 × 10−3 | Extracellular space | 12 | 4.40 × 10−5 | Ribonuclease activity | 2 | 4.12 × 10−2 | NA | NA | NA |
Brown | Inflammatory response | 68 | 1.05 × 10−10 | Extracellular exosome | 346 | 3.36 × 10−24 | Protein binding | 810 | 2.55 × 10−11 | Osteoclast differentiation | 43 | 1.90 × 10−12 |
Tan | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 6 | 8.89 × 10−10 | MHC class II protein complex | 6 | 3.36 × 10−9 | MHC class II receptor activity | 5 | 1.17 × 10−7 | Asthma | 6 | 8.95 × 10−8 |