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Table 3 Minor allele frequencies of investigated SNPs in general population (controls), as reported for IBD (IBD) and in the IBD cohort described here (cohort)

From: Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease

Treatment SNP MAF controls [31] MAF IBD [31] MAF cohort
IRGM C 0.13 0.18 0.14
ATG16L1 T 0.48 0.40 [44] 0.57
NOD2 T, C, C  
rs2066844 T 0.07 0.14 0.07
rs2066845 C 0.01 0.05 0.03
rs2066847 C 0.02 0.11 0.04
XBP1 C, protective 0.04 0.04 0.05
LRRK2/MUC19 T 0.02 0.03 0.03
CCR6 A 0.47 0.48 0.50
IL23R G, protective 0.08 0.02 0.04
STAT3 T 0.42 0.41 0.38
NCF4 C 0.33 0.38 [31, 45, 46] 0.31
  1. MAF minor allele frequency, SNP single nucleotide polymorphism