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Table 3 Biomarkers for checkpoint inhibitors: prognostic (in italics) and predictive details

From: Future perspectives in melanoma research “Melanoma Bridge”, Napoli, November 30th–3rd December 2016

Ipilimumab

Pembrolizumab

Lactate dehydrogenase

Stage III-IVB/IVC

Relative lymphocyte counts (RLC)

Lactate dehydrogenase (LDH)

Absolute eosinophil counts (AEC)

Relative lymphocyte counts (RLC)

Absolute monocyte counts (AMC)

Relative eosinophil counts (REC)

Tregs: unknown

 

MDSC: unknown

 

γδ T-cells: uncertain

 

Increase CD4+ CD8+ T cell: uncertain