Table 1 Classification criteria
Classification | ALT | HBV DNA | HBeAg |
|---|---|---|---|
Disease phases classification | |||
 Immune active (IA) | Elevated | > 20,000 IU/mL | Positive |
>Â 2000Â IU/mL | Negative | ||
 Inactive CHB (IC) | Normal | Low HBV DNA level | Negative |
 Immune tolerance (IT) | Normal | > 1 million IU/mL | Positive |
 Grey zone (GZ) | Not classified as IC, IT or IA | ||
Treatment classification | |||
 CHB patients who are recommended to initiate antiviral therapy (CA) | > 2 ULN | > 20,000 IU/mL | Positive |
>Â 2000Â IU/mL | Negative | ||
 CHB patients who are not strongly recommended to be given antiviral therapy (CAN) | Patients did not meet CA criteria | ||