Table 3 Detection of the different platelet autoantibodies in ITP, non-ITP and healthy controls
Autoantibody category | ITP (n = 201) | Non-ITP (n = 126) | Healthy controls (n = 207) | ||
|---|---|---|---|---|---|
Newly-diagnosed (n = 63) | Persistent (n = 60) | Chronic (n = 78) | |||
Anti-GPIX antibody (ng/mL) | 107.47 ± 81.68†‡§ | 93.91 ± 47.44†‡§ | 79.78 ± 56.41‡§ | 59.98 ± 23.46 | 52.89 ± 21.27 |
Anti-GPIb antibody (ng/mL) | 159.04 ± 104.39*†‡§ | 134.52 ± 57.33†‡§ | 104.84 ± 36.91§ | 95.32 ± 27.44 | 86.28 ± 26.91 |
Anti-GPIIIa antibody (ng/mL) | 128.24 ± 69.70*†‡§ | 94.60 ± 26.33‡§ | 89.19 ± 24.70‡§ | 72.41 ± 20.93 | 70.26 ± 23.29 |
Anti-GPIIb antibody (ng/mL) | 154.63 ± 126.02*†‡§ | 94.17 ± 28.82‡§ | 98.54 ± 49.70‡§ | 74.36 ± 21.15 | 69.83 ± 23.23 |
Anti-P-selectin antibody (ng/mL) | 145.18 ± 73.89*†‡§ | 124.92 ± 66.15‡§ | 129.26 ± 68.73‡§ | 73.29 ± 24.18 | 72.29 ± 25.31 |