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Table 3 Detection of the different platelet autoantibodies in ITP, non-ITP and healthy controls

From: Flow cytometric immunobead assay for quantitative detection of platelet autoantibodies in immune thrombocytopenia patients

Autoantibody category ITP (n = 201) Non-ITP (n = 126) Healthy controls (n = 207)
Newly-diagnosed (n = 63) Persistent (n = 60) Chronic (n = 78)
Anti-GPIX antibody (ng/mL) 107.47 ± 81.68†‡§ 93.91 ± 47.44†‡§ 79.78 ± 56.41‡§ 59.98 ± 23.46 52.89 ± 21.27
Anti-GPIb antibody (ng/mL) 159.04 ± 104.39*†‡§ 134.52 ± 57.33†‡§ 104.84 ± 36.91§ 95.32 ± 27.44 86.28 ± 26.91
Anti-GPIIIa antibody (ng/mL) 128.24 ± 69.70*†‡§ 94.60 ± 26.33‡§ 89.19 ± 24.70‡§ 72.41 ± 20.93 70.26 ± 23.29
Anti-GPIIb antibody (ng/mL) 154.63 ± 126.02*†‡§ 94.17 ± 28.82‡§ 98.54 ± 49.70‡§ 74.36 ± 21.15 69.83 ± 23.23
Anti-P-selectin antibody (ng/mL) 145.18 ± 73.89*†‡§ 124.92 ± 66.15‡§ 129.26 ± 68.73‡§ 73.29 ± 24.18 72.29 ± 25.31
  1. * p < 0.05 vs. Persistent ITP group with the same antibody
  2. † p < 0.05 vs. Chronic ITP group with the same antibody
  3. ‡ p < 0.01 vs. Non-ITP group with the same antibody
  4. § p < 0.01 vs. Healthy controls group with the same antibody