Fig. 6

L91 induces proliferation, activation and generation of memory CD4 T cells of BCG vaccinated volunteers. PBMCs from healthy BCG immunized individuals were stimulated with L91 and control cultures with F91, Pam2Cys or media alone for 96 h and cells were analyzed for a proliferation by ³H-thymidine incorporation (n = 20); b contour plots and c scatter dot plot shows percentage population of CD25 expressing CD4 T cells on in vitro stimulation with L91 (n = 18). The data in the inset of dot plots illustrate Mean ± SEM of CD25⁺ CD4 positive cells. Each dot in scatter plots corresponds to one human subject. Data are shown as Mean ± SEM. ***p ≤ 0.0005, ***p ≤ 0.0005, ns not significant