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Table 3 Parameter sets with corresponding characteristics of the ten best-fit simulations for the 2008–2009 influenza season

From: Data-driven interdisciplinary mathematical modelling quantitatively unveils competition dynamics of co-circulating influenza strains

Set Parameters Characteristics
  R a0max R a0min RF b Z CC c Y I Y peak (day)d I Z peak (day)e I Z max/I f Y max I Y *I Z (day)g Correlation coefficient (%) R heZ R ieY\Z
1 2.00 1.61 1.00 0.71 167 307 21.93 210 96.96 1.65 0.75
2 2.00 1.61 1.00 0.72 167 307 21.95 209 96.96 1.65 0.75
3 2.00 1.61 1.00 0.73 167 307 21.98 209 96.95 1.65 0.75
4 2.01 1.61 1.00 0.67 167 307 21.81 213 96.95 1.65 0.75
5 2.00 1.61 1.00 0.74 167 307 22.00 208 96.95 1.65 0.75
6 2.01 1.61 1.00 0.68 167 307 21.84 213 96.94 1.65 0.75
7 2.00 1.61 1.00 0.75 167 307 22.02 207 96.94 1.65 0.75
8 2.01 1.61 1.00 0.69 167 307 21.87 212 96.94 1.65 0.75
9 2.01 1.61 1.00 0.70 167 307 21.90 211 96.93 1.65 0.75
10 2.01 1.61 1.00 0.71 167 307 21.93 210 96.92 1.65 0.75
GM           1.65 0.75
GSD           1.00 1.00
  1. 13965 simulations were performed with the parameters R 0max, R 0min, RF Z , and CC Y set within each specified range. 10 best-fit simulations were selected based on the correlation coefficient between the simulated epidemic curve and the observed weekly A/H1N1 IVIR curve. Pearson method was used to estimate the correlation coefficient
  2. GM geometric mean, GSD geometric standard deviation
  3. a R 0max and R 0min defined the range of the basic reproductive number [25]
  4. b RF Z represented relative fitness of clade Z
  5. c CC Y represented competition cost of clade Y
  6. d I Ypeak denoted the peak day of clade Y epidemic which was manifested by the infectives of clade Y
  7. e I Zpeak denoted the peak day of clade Z epidemic which was manifested by the infectives of clade Z
  8. f I Zmax /I Ymax denoted the height ratio of clade Z epidemic to clade Y epidemic
  9. g I Y *I Z denoted the crossing day of clade Z epidemic with clade Y epidemic
  10. h R eZ estimated the annual effective reproductive number of clade Z
  11. i ReY\Z estimated the annual effective reproductive number of clade Y in the presence of clade Z