Skip to main content

Table 1 Summary of model parameter values

From: Data-driven interdisciplinary mathematical modelling quantitatively unveils competition dynamics of co-circulating influenza strains

Parameter Meaning Value Source/comment
R 0max, R 0min Defining the range of the basic reproductive number See Ref. [25] The simulations were performed with the parameters R 0max set ranging from 2.40 to 1.20 and R 0min set ranging from R 0max to 0.80
Temp Mean temperature See Additional file 4: Table S3 Taiwan Central Weather Bureau (http://www.cwb.gov.tw/V7/climate/monthlyData/mD.htm)
RH Mean relative humidity See Additional file 4: Table S3 Taiwan Central Weather Bureau (http://www.cwb.gov.tw/V7/climate/monthlyData/mD.htm)
AP Atmospheric pressure See Additional file 4: Table S3 Taiwan Central Weather Bureau (http://www.cwb.gov.tw/V7/climate/monthlyData/mD.htm)
RF Relative fitness Estimated In terms of transmissibility, representing the strain fitness of a clade as compared with the reference clade
CC Competition cost Estimated In terms of transmissibility, addressing the reduction in strain fitness associated with the interaction between two clades
λ[i] Force of infection to age group i Estimated  
θ Transition rate from exposed state to infective state 1/day Probability of the exposed to become infective per unit of time; assuming latent period around 1 day [26]
α Recovery rate 0.2/day Probability of the infectives to become recovered and immune per unit of time; assuming infectious period around 5 days [26]
ν Proportion of susceptibles becoming immune 15 days after vaccination See Additional file 5: Table S4, for the progress of annual vaccination program As the simulated clades were predominantly reported as low reactors to the contemporaneous annual vaccine strains, the model assumed 50% of the vaccinees were protected from infection of the contemporaneous seasonal strains [28, 29]. The assumption was relaxed in the process of assessing the impacts of the annual vaccination program on the 2008–2009 seasonal influenza epidemic (see the “Results” section)