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Table 1 d-Lactic acidosis case reports screened for qualitative synthesis

From: Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review

Episode code # References Included Reasons for exclusion
1 [20] N d-Lactate measurement not specified
2 [17] N Plasma d-lactate within normal range
3 [21] N d-Lactate measurement not specified
4 [22] Y  
5 [23] N d-Lactate measurement not specified
6 [24] Y  
7 [25] N d-Lactate not d-la; No comparison between d-lactate and neurological symptoms
8 [26] Y  
9 [27] Y  
10 [28] Y  
11 [29] Y  
12a and 12b [30] Y  
13 [31] Y  
14 [32] Y  
15 [33] Y  
161 and 162 [34] Y  
17 [35] Y  
18 [36] Y  
19 [37] Y  
20 [38] Y  
21 [39] Y  
22 [15] N d-Lactate levels not presented in relation to neurological symptoms
23 [40] Y  
24 [41] Y  
25 [42] Y  
26* [43] Y  
27 [44] Y  
28 [45] Y  
29 [46] Y  
30 [47] Y  
31 [48] Y  
32 [49] N Unable to obtain full-text
33 [50] Y  
341 and 342 [51] Y  
35 [52] Y  
36* [53] Y  
37 [54] Y  
38 [55] N Neurological symptoms not specified
39* [56] Y  
40 [57] Y  
41 [58] Y  
42* [59] Y  
43 [60] Y  
44 [11] Y  
45 [61, 62] N Same case for both references; d-lactate levels not specified
46 [63] N d-Lactate not measured
47a and 47b [64] Y  
48 [65] Y  
49 [66] Y  
50 [67] Y  
51a and 51b [68] Y  
52 [69] Y  
53 [70] Y  
54 [71] N Unable to obtain English full-text
55 [72] Y  
56 [73] Y  
57 [74] Y  
58a and 58b [75] Y  
59 [76] Y  
60 [77] Y  
61 [78] N d-Lactate measurement not specified
62 [79] Y  
63 [80] N Neurological symptoms not specified
64 [16] Y  
65 [81] Y  
66 [82] Y  
67 [83] N d-Lactate only measured during intervention
  1. Subscript numbers (1 and 2) indicate separate episodes for the same patient. The letters a and b identify different patient cases reported in the same reference. Episodes from non-SBS patients are marked with an asterisk. Episodes included in qualitative synthesis simultaneously reported at least one high D-lactate level (from blood or urine analysis) and documented neurological symptoms