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Table 4 Cytokine levels in pancreatic tissue lysates from total AIP, CP and PDAC patients

From: Distinct pathophysiological cytokine profiles for discrimination between autoimmune pancreatitis, chronic pancreatitis, and pancreatic ductal adenocarcinoma

Cytokine Compared groups
1st group vs 2nd group
Median conc. (pg/mg)
of 1st group/IQR/n
Median conc. (pg/mg)
of 2nd group/IQR/n
p-value
IL-1β AIP vs CP
AIP vs PDAC
2.69/4.57/12
2.69/4.57/12
1.71/1.31/12
2.01/4.29/12
0.1332
0.3708
IL-6 AIP vs CP
AIP vs PDAC
12.82/40.48/11
12.82/40.48/11
12.62/28.80/12
40.6/73.42/12
0.8055
0.2549
IL-7 AIP vs CP
AIP vs PDAC
2.9/1.72/11
2.9/1.72/11
4.46/2.08/12
4.01/4.28/12
0.1090
0.4036
IL-8 AIP vs CP
AIP vs PDAC
17.82/338.64/12
17.82/338.64/12
27.25/70.63/12
105.30/138.65/12
0.9770
0.0304
IL-10 AIP vs CP
AIP vs PDAC
0.59/0.72/12
0.59/0.72/12
1.05/0.63/12
0.92/0.51/12
0.0732
0.2713
IL-13 AIP vs CP
AIP vs PDAC
4.7/7.15/11
4.7/7.15/11
8.87/8.01/12
8.56/5.81/12
0.0694
0.2064
IL-17 AIP vs CP
AIP vs PDAC
21.93/27.03/12
21.93/27.03/12
10.64/12.12/12
21.2/25.98/11
0.0120
0.4789
G-CSF AIP vs CP
AIP vs PDAC
9.56/11.67/12
9.56/11.67/12
1.98/8.64/12
3.44/7.40/12
0.1080
0.2790
IFN-γ AIP vs CP
AIP vs PDAC
7.02/27.31/12
7.02/27.31/12
25.7/17.67/12
19.50/20.66/12
0.0815
0.2167
MCP-1 AIP vs CP
AIP vs PDAC
303.70/509.70/12
303.70/509.70/12
158.94/206.72/12
140.45/286.84/12
0.1260
0.2145
MIP-1 β AIP vs CP
AIP vs PDAC
224.20/354.68/12
224.20/354.68/12
90.17/132.30/12
112.90/277.46/12
0.0326
0.3708
TNF-α AIP vs CP
AIP vs PDAC
6.01/2.89/12
6.01/2.89/12
12.60/10.13/12
8.97/17.84/12
0.0038
0.0086
  1. Concentrations are expressed in pg/mg total protein
  2. Italic values indicate significance of p value (p < 0.05)
  3. IQR interquartile range, n number of observations