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Table 2 Predictor of dengue disease severity

From: Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease

 

Univariate

Multivariate

Coef. (95% CI)

P value

Coef. (95% CI)

P value

Febrile phase

 Platelet count

0.997 (0.998, 1.005)

0.431

–

–

 VEGF

1.005 (0.996, 1.014)

0.259

–

–

 IL-18 (per 10 unit)

1.036 (1.015, 1.058)

0.001**

1.032 (1.006, 1.059)

0.017*

 LBP (per 1000 unit)

1.131 (1.073, 1.191)

0.0001***

1.106 (1.002, 1.198)

0.013*

 sCD14 (per 100 unit)

1.195 (1.114, 1.282)

0.0001***

1.106 (1.022, 1.198)

0.013*

Defervescence phase

 Platelet count

0.998 (0.990, 1.006)

0.694

–

–

 IL-18 (per 10 unit)

1.003 (1.001, 1.006)

0.02*

1.003 (1, 1.006)

0.048*

 CXCL6

1.01 (0.995, 1.026)

0.205

–

–

 IL-10

1 (0.997, 1.003)

0.956

–

–

 IP-10

1 (1, 1)

0.517

–

–

  1. Associations of plasma biomarkers at febrile and defervescence phase with the severity of dengue disease. By using binary regression model, variables that showed a significant relationship with the development of dengue with warning signs and severe dengue in univariate model will then be included in the multivariate model. The Hosmer–Lemeshow value for this model was P = 0.743
  2. * P < 0.05
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Journal of Translational Medicine

ISSN: 1479-5876

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