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Table 2 Predictor of dengue disease severity

From: Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease

  Univariate Multivariate
Coef. (95% CI) P value Coef. (95% CI) P value
Febrile phase
 Platelet count 0.997 (0.998, 1.005) 0.431
 VEGF 1.005 (0.996, 1.014) 0.259
 IL-18 (per 10 unit) 1.036 (1.015, 1.058) 0.001** 1.032 (1.006, 1.059) 0.017*
 LBP (per 1000 unit) 1.131 (1.073, 1.191) 0.0001*** 1.106 (1.002, 1.198) 0.013*
 sCD14 (per 100 unit) 1.195 (1.114, 1.282) 0.0001*** 1.106 (1.022, 1.198) 0.013*
Defervescence phase
 Platelet count 0.998 (0.990, 1.006) 0.694
 IL-18 (per 10 unit) 1.003 (1.001, 1.006) 0.02* 1.003 (1, 1.006) 0.048*
 CXCL6 1.01 (0.995, 1.026) 0.205
 IL-10 1 (0.997, 1.003) 0.956
 IP-10 1 (1, 1) 0.517
  1. Associations of plasma biomarkers at febrile and defervescence phase with the severity of dengue disease. By using binary regression model, variables that showed a significant relationship with the development of dengue with warning signs and severe dengue in univariate model will then be included in the multivariate model. The Hosmer–Lemeshow value for this model was P = 0.743
  2. * P < 0.05