Skip to main content

Table 2 Significantly expressed miRNAs in the atrial myocardial tissue of patients with CHD after CPB (n = 3) compared to before CPB (n = 3) as determined by microarray

From: Differential expression of microRNAs following cardiopulmonary bypass in children with congenital heart diseases

miRNA Median before CPB Median after CPB STDV before CPB STDV after CPB Fold change Regulation P-value
miR-4750-5p 1.67 8.60 2.59 4.24 5.26 Up 0.0399
miR-6134 1.00 3.08 0.46 0.78 3.03 Up 0.0215
miR-6873-3p 2.49 6.29 0.29 1.31 2.50 Up 0.0441
miR-4747-5p 1.07 2.38 0.78 1.05 2.22 Up 0.0151
miR-5195-5p 1.48 3.04 0.49 0.91 2.04 Up 0.0213
miR-6074 1.50 3.00 1.14 1.52 2.00 Up 0.0252
miR-6751-3p 2.89 5.68 0.33 1.12 1.96 Up 0.0323
miR-328-5p 15.50 28.90 4.82 3.56 1.85 Up 0.0263
miR-6792-5p 2.42 4.40 0.56 1.34 1.82 Up 0.0485
miR-4514 1.65 2.93 0.80 0.61 1.79 Up 0.0333
miR-4538 3.31 5.83 1.60 1.37 1.75 Up 0.0033
miR-6870-5p 2.31 3.91 1.63 1.88 1.69 Up 0.0102
miR-7156-5p 1.25 2.12 0.61 0.61 1.69 Up 0.0300
miR-4447 1.64 2.73 0.44 0.19 1.67 Up 0.0369
miR-6769b-5p 20.56 33.29 3.95 4.51 1.61 Up 0.0442
miR-7846-3p 5.11 8.12 1.69 2.65 1.59 Up 0.0398
miR-1261 1.90 2.98 1.58 2.01 1.56 Up 0.0353
miR-6740-5p 39.53 61.77 6.38 14.38 1.56 Up 0.0489
miR-6746-5p 3.75 5.79 1.03 1.20 1.54 Up 0.0265
miR-645 1.56 2.42 0.93 0.70 1.54 Up 0.0455
miR-2113 1.46 2.20 0.47 0.74 1.52 Up 0.0437
miR-497-3p 1.46 2.14 0.29 0.51 1.47 Up 0.0280
miR-648 1.64 2.39 0.55 0.44 1.47 Up 0.0497
miR-5088-5p 9.24 13.26 1.59 2.19 1.43 Up 0.0379
miR-3945 3.43 4.81 0.97 0.98 1.41 Up 0.0342
miR-4468 2.07 2.84 0.55 0.62 1.37 Up 0.0289
miR-1471 6.69 9.07 2.16 2.11 1.35 Up 0.0464
miR-5006-5p 21.99 28.90 2.45 3.83 1.32 Up 0.0108
miR-198 3.59 4.49 1.04 1.32 1.25 Up 0.0404
miR-770-5p 9.59 3.17 1.11 1.81 3.03 Down 0.0095
miR-4261 35.83 14.45 1.98 7.10 2.48 Down 0.0183
miR-874-5p 15.30 6.57 1.76 3.12 2.33 Down 0.0102
miR-550a-5p 5.57 2.44 1.67 1.10 2.29 Down 0.0114
miR-3651 53.15 23.24 5.23 9.24 2.29 Down 0.0455
miR-6865-3p 8.00 3.55 1.51 1.76 2.26 Down 0.0108
miR-222-3p 14.15 6.51 1.03 2.80 2.17 Down 0.0308
miR-3607-3p 8.69 4.10 0.70 1.25 2.12 Down 0.0424
miR-1304-3p 9.97 4.71 1.98 0.36 2.12 Down 0.0469
miR-6508-5p 9.27 4.41 2.31 1.58 2.10 Down 0.0358
miR-6800-3p 10.18 5.06 2.12 2.07 2.01 Down 0.0182
miR-6861-3p 6.13 3.09 0.74 0.86 1.99 Down 0.0139
miR-212-3p 25.83 13.01 2.76 6.93 1.99 Down 0.0294
miR-6737-3p 11.31 5.76 2.96 1.67 1.96 Down 0.0293
miR-6820-5p 37.19 19.53 0.20 4.42 1.90 Down 0.0238
miR-6792-3p 6.60 3.47 1.06 1.47 1.90 Down 0.0366
miR-3616-3p 6.92 3.68 1.31 1.75 1.88 Down 0.0082
miR-3162-3p 10.75 5.79 2.89 2.53 1.86 Down 0.0029
miR-423-3p 9.21 4.94 1.09 1.21 1.86 Down 0.0056
miR-5190 10.43 5.68 0.59 0.86 1.84 Down 0.0172
miR-4725-5p 8.95 4.90 1.35 2.34 1.83 Down 0.0421
miR-744-5p 9.67 5.32 1.56 1.98 1.82 Down 0.0308
miR-6829-5p 48.68 26.75 3.55 8.52 1.82 Down 0.0360
miR-6889-3p 8.18 4.51 1.73 1.02 1.82 Down 0.0432
miR-4433a-5p 8.38 4.62 2.04 1.02 1.81 Down 0.0276
miR-6813-3p 7.19 4.06 2.29 1.01 1.77 Down 0.0343
miR-4649-3p 9.50 5.47 3.12 2.42 1.74 Down 0.0093
miR-6763-3p 7.94 4.62 1.52 1.52 1.72 Down 0.0434
miR-532-3p 18.58 10.78 0.43 3.99 1.72 Down 0.0487
miR-6769a-5p 11.01 6.45 1.97 1.02 1.71 Down 0.0219
miR-193b-3p 74.91 43.92 26.81 34.56 1.71 Down 0.0341
miR-331-5p 2.64 1.58 0.28 0.62 1.67 Down 0.0446
miR-6858-3p 8.53 5.15 2.59 2.47 1.66 Down 0.0017
miR-564 17.68 10.75 2.27 3.32 1.65 Down 0.0099
miR-6723-5p 26.08 16.14 2.83 6.35 1.62 Down 0.0352
miR-28-3p 4.85 3.02 0.21 0.58 1.61 Down 0.0187
miR-339-3p 13.22 8.22 1.98 2.36 1.61 Down 0.0275
miR-23c 5.83 3.62 1.59 0.81 1.61 Down 0.0378
miR-93-5p 114.26 70.98 9.72 24.81 1.61 Down 0.0488
miR-6752-3p 5.76 3.67 1.11 0.79 1.57 Down 0.0329
miR-766-3p 10.39 6.64 1.38 2.07 1.56 Down 0.0125
miR-1306-5p 4.68 3.05 0.44 0.67 1.54 Down 0.0074
miR-6798-3p 4.49 2.92 0.87 1.04 1.54 Down 0.0141
miR-664a-3p 17.21 11.20 1.39 3.72 1.54 Down 0.0362
miR-208a-5p 45.35 29.37 7.47 13.45 1.54 Down 0.0450
miR-6880-3p 6.55 4.43 2.43 1.74 1.48 Down 0.0272
miR-143-3p 327.88 223.74 43.81 69.68 1.47 Down 0.0425
miR-624-5p 3.66 2.49 0.37 0.53 1.47 Down 0.0447
miR-210-5p 4.05 2.86 0.41 0.39 1.42 Down 0.0101
miR-6073 5.18 3.67 1.17 1.43 1.41 Down 0.0140
miR-374c-5p 11.99 8.54 1.55 2.75 1.40 Down 0.0378
miR-4484 27.73 20.62 1.81 1.80 1.34 Down 0.0000
miR-4664-3p 5.01 3.75 0.50 0.61 1.34 Down 0.0096
miR-6731-3p 4.38 3.26 1.21 1.48 1.34 Down 0.0399
miR-4769-3p 6.46 5.11 1.50 1.35 1.26 Down 0.0213
miR-15a-3p 3.49 2.79 0.34 0.28 1.25 Down 0.0114
hsa-let-7a-3p 3.24 2.59 0.35 0.29 1.25 Down 0.0172
miR-26b-3p 3.15 2.54 0.72 0.55 1.24 Down 0.0244
miR-940 32.01 26.08 7.78 6.20 1.23 Down 0.0218
miR-3189-3p 3.61 3.01 0.44 0.33 1.20 Down 0.0153
miR-29a-5p 3.05 2.53 0.16 0.28 1.20 Down 0.0166
  1. Each value represents the median of three patients before and after CBP and ±standard deviation (STDV). Statistical analysis was performed with paired-two-tailed t-test (P < 0.05)