Table 5 The number of target genes regulated by the differentially expressed miRNAs in the dysregulated pathways
From: Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages
Pathways | Differentially expressed miRNA | Number target genes |
|---|---|---|
Bacterial invasion pathway | hsa-miR-484 | 15 |
hsa-miR-6848- | 4 | |
hsa-miR-5094 | 1 | |
hsa-miR-425-5p | 9 | |
hsa-miR-1293 | 2 | |
hsa-miR-4488-5p | ||
hsa-miR-1224-5p | 1 | |
hsa-miR-4732- | 1 | |
Fatty acid biosynthesis pathways | hsa-miR-1293 | 1 |
hsa-miR-484 | 1 | |
hsa-miR-425-5p | 1 | |
Fatty acid metabolism | hsa-miR-5094 | 2 |
hsa-miR-425-5p | 4 | |
hsa-miR-1293 | 3 | |
hsa-miR-484 | 4 | |
hsa-miR-6849- | 1 | |
Trp/phe synthesis | hsa-miR-6848- | 1 |
hsa-miR-4467 | 1 | |
hsa-miR-484 | 2 | |
Fatty acid elongation | hsa-miR-425-5p | 4 |
hsa-miR-484 | 2 | |
hsa-miR-5094 | 1 | |
Central carbon metabolism | hsa-miR-1224-5p | 5 |
hsa-miR-484 | 10 | |
Has-mir-96 | ||
hsa-miR-425-5p | 6 | |
hsa-miR-6848- | 1 | |
hsa-miR-6849- | 1 | |
Steroid biosynthesis | hsa-miR-484 | 4 |
hsa-miR-4732- | 1 | |
hsa-miR-425-5p | 3 | |
Glucose amino glycan | hsa-miR-484 | 4 |
hsa-miR-6848- | 2 | |
hsa-miR-5094 | 1 | |
hsa-miR-1293 | 1 | |
hsa-miR-1224-5p | 1 | |
hsa-miR-6849- | 1 | |
2′-Oxycarboxyl | hsa-miR-484 | 4 |
Has-miR-96 | ||
hsa-miR-6848- | 2 | |
hsa-miR-5094 | 1 | |
hsa-miR-1293 | 1 | |
hsa-miR-1224-5p | 1 | |
hsa-miR-6849- | 1 | |
Val/leu/isoleu synthesis | hsa-miR-484 | 5 |
hsa-miR-4732- | 2 | |
hsa-miR-5094 | 3 | |
hsa-miR-425-5p | 1 | |
hsa-miR-4467 | 1 | |
hsa-miR-1293 | 1 | |
Proteoglycan | hsa-miR-5094 | 5 |
hsa-miR-484 | 27 | |
hsa-miR-425-5p | 17 | |
hsa-miR-1293 | 2 | |
hsa-miR-1224-5p | 4 | |
hsa-miR-4732- | 2 | |
hsa-miR-6849- | 3 | |
hsa-miR-6848- | 4 | |
Lysine degradation | hsa-miR-484 | 11 |
hsa-miR-5094 | 3 | |
hsa-miR-1293 | 4 | |
hsa-miR-425-5p | 4 | |
hsa-miR-6848- | 1 | |
hsa-miR-1224-5p | 1 |