Table 1 Summary of AAV variants and mouse strains tested
From: Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models
Serotype | (Y-F) | (T-V) | (K-E) | Mouse |
|---|---|---|---|---|
AAV2-(Y-F)-M3 | 444, 500, 730 | Â | Â | C57BL/6 |
AAV2-(Y-F)-M3-T491V | 444, 500, 730 | 491 | Â | C57BL/6 |
AAV2-(Y-F)-M3-(T491+550V) | 444, 500, 730 | 491 and 550 | Â | C57BL/6 |
AAV2-K544E | Â | Â | 544 | C57BL/6 |
AAV2-K556E | Â | Â | 556 | C57BL/6 |
AAV2-LiA | 444 and 500 | Â | Â | BALB/c-HB |
AAV2-LiC | 500 | Â | Â | BALB/c-HB |
AAV8 | Â | Â | Â | C57BL/6 |
AAV8-T494V | Â | 494 | Â | C57BL/6 |
AAV8-(Y275+447+733F) | 275, 447, and 733 | Â | Â | C57BL/6 |