Table 3 Expression of M1 and M2 makers in omentum and liver biopsy samples
Target genes expression in obese biopsy samples (33) | Obese non-diabetics (16) | Obese diabetics (17) | Correlation (R); p value | |
|---|---|---|---|---|
Omentum | ||||
 TREM-1 | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
 CD68 | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
 CD86 | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
 CCR-7 | 29 (88.7%) | 12 (75%) | 17 (100%)* | R = 0.383; p = 0.044 |
 iNOS | 29 (88.7%) | 12 (75%) | 17 (100%)* | R = 0.436; p = 0.018 |
 IFNγ | 28 (84.8%) | 11 (68.8%) | 17 (100%)**** | R = 0.631; p < 0.0001 |
 TNF-α | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
 IL-6 | 29 (88.7%) | 13 (81.3%) | 16 (94.1%) | NS |
 TREM-2 | 30 (90.9%) | 13 (81.3%) | 17 (100%) | NS |
 CD206 | 29 (88.7%) | 12 (75%) | 17 (100%)* | R = 0.383; p = 0.044 |
 CD163 | 30 (90.9%) | 13 (81.3%) | 17 (100%) | NS |
 IL-4 | 27 (81.8%) | 10 (62.5%) | 17 (100%)** | R = 0.486; p = 0.007 |
 IL-10 | 27 (81.8%) | 10 (62.5%) | 17 (100%)** | R = 0.486; p = 0.007 |
 MCP-1 | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
 CCR-2 | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
 CCR-5 | 31 (93.9%) | 14 (87.5%) | 17 (100%) | NS |
Liver | ||||
 TREM-1 | 26 (78.7%) | 9 (56.3%) | 17 (100%)** | R = 0.535; p = 0.003 |
 CD68 | 23 (69.6%) | 6 (37.5%) | 17 (100%)**** | R = 0.680; p < 0.0001 |
 CD86 | 23 (69.6%) | 6 (37.5%) | 17 (100%)**** | R = 0.680; p < 0.0001 |
 CCR-7 | 22 (66.6%) | 5 (31.3%) | 17 (100%)**** | R = 0.729; p < 0.0001 |
 iNOS | 22 (66.6%) | 5 (31.3%) | 17 (100%)**** | R = 0.729; p < 0.0001 |
 IFNγ | 24 (72.7%) | 7 (43.8%) | 17 (100%)**** | R = 0.631; p < 0.0001 |
 TNF-α | 24 (72.7%) | 6 (37.5%) | 15 (88.2%)** | R = 0.527; p = 0.003 |
 IL-6 | 18 (54.5%) | 6 (37.5%) | 12 (70.6%) | NS |
 TREM-2 | 23 (69.6%) | 10 (62.5%) | 13 (76.5%) | NS |
 CD206 | 20 (60.6%) | 4 (25%) | 16 (94.1%)**** | R = 0.707; p < 0.0001 |
 CD163 | 15 (45.4%) | 2 (12.5%) | 13 (76.5%)**** | R = 0.642; p < 0.0001 |
 IL-4 | 23 (69.6%) | 6 (37.5%) | 17 (100%)**** | R = 0.680; p < 0.0001 |
 IL-10 | 14 (42.4%) | 4 (25%) | 10 (58.8%) | NS |
 MCP-1 | 23 (69.6%) | 6 (37.5%) | 17 (100%)**** | R = 0.680; p < 0.0001 |
 CCR-2 | 23 (69.6%) | 6 (37.5%) | 17 (100%)**** | R = 0.680; p < 0.0001 |
 CCR-5 | 23 (69.6%) | 6 (37.5%) | 17 (100%)**** | R = 0.680; p < 0.0001 |