Fig. 5

The improvement of MASCT-induced immune responses in tumor recurrence-free HCC patients. a The frequency of Tregs in tumor recurrence-free HCC patients’ PBMCs was lower than that in tumor recurred patients. b The MASCT-induced antigen peptide pool-specific immune responses in tumor recurrence-free patients were stronger than the immune responses in patients with tumor recurrence. The fold changes of antigen-specific proliferating of T cells were analyzed by comparing patients’ PBMCs stimulated by multiple antigen peptide pool with PBMCs stimulated by irrelevant peptides. The data collected on the last time point were used for the analysis. The results were shown in mean ± SD. Two-sample t test was used for statistical analysis. *p < 0.05