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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy

Fig. 4

B cell repertoires after rituximab. B cell repertoires after rituximab in two controls, eight non-responders (N) and nine responders (R) before and after rituximab. a The fraction unique sequences detected in each sample after subsampling to 1000 molecules. b The change in the fraction of unique sequence in the N and R groups. c The relative abundance of molecules with switched isotypes. d The change in abundance of the N and R groups. e Mutation frequency for switched and non-switched isotypes. f The change in non-switched mutation frequency for N and R groups. Samples from the same candidate are connected by a line

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