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Table 2 Lymph node characteristics and OSNA results

From: Lymph node pooling: a feasible and efficient method of lymph node molecular staging in colorectal carcinoma

  Median (IQR) p-value
OSNA pooling cohort OSNA individual cohort  
Fresh LN 18.0 (13.0–25.0) 13.0 (10.0–18.0) <0.001
FFPE LN 1.0 (0.0–5.0) 3.0 (2.0–5.0) <0.001
Total LN 20.5 (17.0–27.0) 17.0 (13.0–22.0) <0.001
H&E results (pN)    
 pN0 77 (89.5) 92 (90.2) 0.588
 Positive 9 (10.5) 10 (9.8)  
  pN1a 3 (3.5) 5 (4.9)  
  pN1b 3 (3.5) 3 (2.9)  
  pN1c 0 0  
  pN2a 1 (1.2) 2 (2.0)  
  pN2b 2 (2.3) 0  
 OSNA results    
  Positive 24 (27.9) 61 (59.8) <0.001
  Negative 62 (72.1) 41 (40.2)  
TTL of OSNA positive cases 5485 (855–26,350) 1940 (920–7400) 0.228
OSNA tests 2.0 (1.0–3.0) 13.0 (10.0–18.0) <0.001
OSNA tests saved 16 (12–22)  
  1. IQR interquartile range, FFPE formalin-fixed, paraffin embedded, LN lymph node