Skip to main content

Advertisement

Table 1 Patient’s demographics and specimen characteristics from the two cohorts

From: Lymph node pooling: a feasible and efficient method of lymph node molecular staging in colorectal carcinoma

Clinical parameter n (%)/median (IQR) p value
OSNA pooling cohort OSNA individual cohort
Cases 86 (100) 102 (100)  
 Gender    0.974
  Male 55 (64.0) 65 (63.7)  
  Female 31 (36.0) 37 (36.3)  
 Age (years) 70.0 (63.0–79.0) 65.5 (59.0–72.0) 0.0635
Tumor characteristics    
 Size (cm) 3.0 (1.7–4.5) 2.5 (1.1–3.7) 0.992
 Location    0.090
  Right colon 39 (45.3) 51 (50.0)  
  Flexures/transverse 1 (1.2) 7 (6.9)  
  Left colon 46 (53.5) 44 (43.1)  
 Gross configuration    0.821
  Polypoid 57 (66.3) 66 (64.7)  
  Ulcerated 29 (33.7) 36 (35.3)  
 Grade    <0.001
  High 49 (57.0) 26 (25.5)  
  Low 37 (43.0) 76 (74.5)  
 Type of tumor    0.118
  Adenoma 6 (7.0) 8 (7.8)  
  Carcinoma in situ 6 (7.0) 17 (16.7)  
  Adenocarcinoma 74 (86.0) 77 (75.5)  
 Budding    0.650
  Absence 13 (17.6) 14 (18.7)  
  Low grade 47 (63.5) 51 (68.0)  
  High grade 14 (18.9) 10 (13.3)  
 Vascular invasion    0.045
  No 65 (75.6) 91 (89.2)  
  Yes 21 (24.4) 11 (10.8)  
 Perineural invasion    0.013
  No 76 (88.4) 98 (96.1)  
  Yes 10 (11.6) 4 (3.9)  
 Tumor deposits    0.165
  No 81 (94.2) 100 (98.0)  
  Yes 5 (5.8) 2 (2.0)  
 pT    0.004
  pT0 6 (7.0) 8 (7.8)  
  pTis 6 (7.0) 17 (16.7)  
  pT1 9 (10.4) 26 (25.6)  
  pT2 16 (18.6) 19 (18.6)  
  pT3 32 (37.2) 24 (23.5)  
  pT4a 17 (19.8) 8 (7.8)  
Lymph nodes    
 Total LN 1992 (100) 1828 (100)  
  Fresh LN 1757 (88.2) 1449 (79.3)  
  FFPE LN 235 (11.8) 379 (20.7)  
  1. IQR interquartile range, LN lymph node, FFPE formalin-fixed paraffin-embedded, p-value: using t test for continuous variables and Chi square for categorical variables