Fig. 7

Histological development of implanted unseeded OptiMaix 2D scaffolds. Six weeks after implantation, the scaffold structure is still dense, but degradation has already started and is proceeding until 32 weeks. Connective tissue is forming on top of the scaffold (EVG) and is lined by newly built urothelium (PanCK). Blood vessels are growing into the artificial collagen (CD34, VEGF) and nerve fibres (S100), which go together with the ingrowth of adjacent muscle tissue (α-SMA). S scaffold, M muscle, CT connective tissue. Scale bar = 50 µm