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Table 3 Safety and tolerability of balixafortide. Subjective rating

From: Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers—results of a dose escalation trial

Side effects in the course of treatment with:

G-CSF

Balixafortide

Abdominal pain

2

0

Bone pain

24

0

Headache

11

1

Skin reactions

1

13

Flu-like symptoms

21

0

Vomiting

0

1

Palpitation

1

0

Fever

2

0

Sweating

0

1

Fatigue

11

4

Insomnia

0

1

The treatment is

 Easy to use

7

29

 Acceptable

13

30

 More convenient overall

2

32